From Redskins Insider:
WR Malcolm Kelly, a second round pick, is out with an ankle injury.
DE Erasmus James, who has not looked very good thus far, is out. He is coming back from major knee surgery and that will take time.
CB Justin Tryon, S Justin Hamilton, G Jason Fabini, OL Chad Rinehart, and DE Rob Jackson are also healthy scratches.
Colt Brennan is the 3rd QB.
WR James Thrash (ankle) will play. The Skins go in with 4 CBs and essentially 3 safeties again, as Kareem Moore is slated for special teams play for now.
For the Cards
RB JJ Arrington, S Oliver Celestin, T Brandon Keith, WR Early Doucet, TE Jerame Tuman, LB Ali Highsmith and DT Gabe Watson are out.