I don't like plain. stripe-less pants for NFL teams...make them look collegiate or less.
A big design thing to me is consistency with striping throughout the uniform. The Skins do it right, look at the sleeve and pant striping.
An example of a team that does it wrong is Dallas. None of the stripes or even colors match the other parts of the uniform, it's like they were designed by different people instead of together as a set. The Giants do the inconsistent striping too. These teams take the uniformity out of the uniforms.